APP涓嬭浇

鏃犺剨妞庡姩鐗╁熀鍥犳柊鍙戠幇鏀瑰啓鍏嶇柅绯荤粺瑙傜偣

2018-07-26 08:32

闀垮簹澶у鐢熺墿鍖诲绯绘暀鎺堝倕宕囧畨锛堝彸锛夋垚鍔熷湪鍔犲窞绱捣鑳嗕腑鎵惧埌AID/APOBEC鍩哄洜锛岄噸鍐欑瀛︾晫瀵瑰厤鐤郴缁熸紨鍖栫湅娉曪紝鏈潵涔熷笇鏈涚户缁杽鐢ㄥ彴婀剧敓鎬佸疂搴撴繁鍏ユ帰绌躲€備腑澶ぞ璁拌€呭惔鐫块獝妗冨洯鎽勩€€107骞?鏈?5鏃?/span>

锛堜腑澶ぞ璁拌€呭惔鐫块獝妗冨洯25鏃ョ數锛夐暱搴氬ぇ瀛︾敓鐗╁尰瀛︾郴鏁欐巿鍌呭磭瀹夛紝鎴愬姛鐨勫湪鍔犲窞绱捣鑳嗕腑鎵惧埌AID/APOBEC鍩哄洜锛屼笉浣嗛噸鍐欑瀛︾晫瀵瑰厤鐤郴缁熸紨鍖栫殑鐪嬫硶锛岀爺绌舵垚鏋滄洿璺冧笂鍥介檯椤跺皷鐨勨€滆嚜鐒堕€氳鈥濇湡鍒娿€?br />
缁忚繃闀胯揪12骞寸殑鐮旂┒锛屽倕宕囧畨 (Sebastian D. Fugmann)鎴愬姛鍦ㄥ姞宸炵传娴疯儐涓壘鍒癆ID/APOBEC鍩哄洜锛屼粬浠婂ぉ鍙楄琛ㄧず锛岃繖绫诲熀鍥犲師鍏堣瀛︾晫璁や负鍙瓨鍦ㄨ緝楂樼瓑鐨勮剨妞庡姩鐗╀腑锛屾媴璐熺紪淇姉浣撱€佺獊鍙樼梾姣掔瓑閲嶄换锛屽睘浜庡悗澶╁厤鐤姏锛屾柊鍙戠幇绛変簬閲嶅啓浜嗙瀛︾晫瀵逛簬鍏嶇柅绯荤粺婕斿寲鐨勭湅娉曘€?br />
鍌呭磭瀹夎〃绀猴紝涓轰綈璇佺爺绌跺彂鐜帮紝鍥㈤槦涔熷杽鐢ㄥ彴婀句赴瀵岀敓鎬佸崗鍔╃爺绌讹紝鐗瑰湴鍓嶅線鏂扮棣欏北婀垮湴锛岄噰闆嗗垎鏋愬悓涓烘棤鑴婃鍔ㄧ墿鐨勬捣璞嗚娊锛屽苟椤哄埄鎵惧埌鐩稿悓鍩哄洜锛屽仛涓哄疄楠屾帹璁哄叿鏈夋櫘閬嶆€х殑鏈夊姏璇佹嵁銆傛澃鍑虹殑鐮旂┒鎴愭灉锛屼篃鍦?鏈?6鏃ョ櫥涓婂浗闄呴《灏栫殑鈥滆嚜鐒堕€氳鈥濇湡鍒?(Nature Communications)銆?br />
鏉ュ彴5骞寸殑寰风睄鏁欐巿鍌呭磭瀹夎〃绀猴紝绱捣鑳嗚繖绫绘棤鑴婃鍔ㄧ墿鐪嬩技鍜岄珮绛夌敓鐗╃浉璺濈敋杩滐紝涓嶈繃浠栦滑瓒呰繃鍗婁笘绾殑瀵垮懡锛屽厤鐤郴缁熶篃椤绘湁鑳藉姏闀挎湡闈㈠寰敓鐗╃殑鎸戞垬銆傚厛鍓嶇瀛︾晫璁や负杩欑被浣庣瓑鐢熺墿鍙湁鍏堝ぉ鍏嶇柅鍔熻兘锛屾病鏈夎剨妞庡姩鐗╀腑鐨勫悗澶╁厤鐤姏锛岀爺绌跺彂鐜扮殑绐佺牬鎬ф垚鏋滐紝瀵逛簬婕斿寲涓婄殑璧锋簮鏈夌潃寰堥噸澶х殑鍚ず銆?br />
鍌呭磭瀹夊湪澶お鏉ㄦ窇鍏冨拰鍥㈤槦鍗忓姪涓嬶紝閫忚繃瀵圭传娴疯儐绛夋棤鑴婃鍔ㄧ墿锛屽皢鍏嶇柅瀛﹀線鍓嶆帹杩涗竴澶ф锛屾湭鏉ュ笇鏈涘杽鐢ㄥ彴婀剧殑鐢熸€佸疂搴擄紝缁х画娣卞叆鎺㈣杩欓」鍩哄洜鍦ㄦ棤鑴婃鍔ㄧ墿鍏嶇柅鍔涗腑鎵紨鐨勫姛鑳斤紝涔熼€忚繃鐮旂┒锛屽惎鍙戝浜庡厤鐤姏杩愪綔鍜岃皟鑺傜殑鏂版兂娉曘€傦紙缂栬緫锛氭潕閿$拫锛?070725

闀垮簹澶у鐢熺墿鍖诲绯绘暀鎺堝倕宕囧畨鎴愬姛鍦ㄥ姞宸炵传娴疯儐涓壘鍒癆ID/APOBEC鍩哄洜锛岄噸鍐欑瀛︾晫瀵瑰厤鐤郴缁熸紨鍖栫湅娉曘€傚浘涓烘捣鑳嗕綋鑵旂粏鑳烇紙鍏嶇柅缁嗚優锛夛紝鍦ㄦ樉寰暅涓嬪憟鐜版牱璨屻€傦紙鍌呭磭瀹夋彁渚涳級涓ぎ绀捐鑰呭惔鐫块獝妗冨洯浼犵湡銆€107骞?鏈?5鏃?/span>

鐩稿叧鏂囩珷

鏈€鏂拌祫璁?/p>

  • Netflix绗笁瀛e鍔?80涓囦粯璐圭敤鎴凤紝鑲′环鍥炴俯
    2019-10-17 13:49
  • 缇庛€佽嫳涓庨煩鍥借仈鎵嬬牬鑾峰叏鐞冩渶澶х殑鏆楃綉鍎跨鑹叉儏缃戠珯
    2019-10-17 13:49
  • Rust瀹夎绋嬪紡鏇存柊閲婂嚭Rustup 1.20锛孉WS鍔犲叆璧炲姪Rust琛屽垪
    2019-10-17 12:49
  • 銆怱A 濡瑰紑绠变笘鐣屻€戞櫤鑳芥竻娲?鍗虫椂褰遍煶浜掑姩 缇庣殑鍚稿皹鏈?I5EXTRA
    2019-10-17 12:49
  • Yahoo瀹e竷灏嗘案涔呭垹闄ahoo Groups鎵€鏈夊唴瀹?/span>
    2019-10-17 10:51

鎵嬫満

  • 浠庤鏍间笂鏉ョ湅 Google Pixel 4 骞朵笉鏄竴娆炬棗鑸版墜鏈?/span>
    2019-10-17 11:47
  • 6400 涓囩敾绱犲洓闀滃ご 绾㈢背 Redmi Note 8 Pro 鍦ㄥ彴涓婂競鍞环浠?6,599 鍏?/span>
    2019-10-16 16:48
  • Pixel 4 XL / Note 10+ / iPhone 11 Pro 鍏鎷嶇収鎯呭瀵规瘮锛氭棩鎷嶃€侀暱鐒︺€佷汉鍍忋€佽€€鍏夈€佸鎷嶃€佸瑙?/span>
    2019-10-16 15:46
  • Google鏂版棗鑸癙ixel 4銆丳ixel 4 XL鐧诲満 鍞环24600銆?9550鍏冭捣銆佷簬10/24寮€鍗?/span>
    2019-10-16 09:48
  • Pixel 4 XL 寮€绠?澶栧瀷銆佸綍闊炽€佹墜鍔挎搷浣滃揩閫熷姩鎵嬬帺
    2019-10-16 06:49

鏁扮爜

  • 鏈€澶?8鑻卞8K鍒嗚鲸鐜?绱㈠凹Z9G鏅鸿兘娑叉櫠鐢佃甯︽潵鈥?/span>
    2019-10-17 11:52
  • 鏇濊胺姝屼笉浼氬湪鍗板害閿€鍞甈ixel 4 鍥犻殧绌烘搷鎺у姛鑳斤紵
    2019-10-17 11:48
  • iQOO Neo 855鐗堟湰灏嗕簬10鏈?4鏃ユ寮忓彂甯?/span>
    2019-10-17 11:53
  • RedmiBook 14閿愰緳鐗堝皢鏀寔鍏ㄦ柊灏忕背浜掍紶锛氬崈寮犫€?/span>
    2019-10-17 11:53
  • 娴蜂俊鏂版満鍏ョ綉宸ヤ俊閮細4850mAh+鍚庣疆鍥涙憚鍍忓ご
    2019-10-17 11:48

绉戞妧

  • 100锛呭睆鍗犳瘮 OPPO鍏ㄩ潰灞忚璁′笓鍒╂洕鍏?/span>
    2018-07-24 14:31
  • 瀵逛笉璧?鎴戞病鏈変綘浠兂鐪嬬殑浠g爜
    2018-07-24 14:31
  • 鍒涙劅绉戞妧锛氫綘鐨勮蛋璺Э鎬佹槸鍚︽殫钘忔潃鏈?鐢ㄨ繖涓狝I浜у搧涓€娴嬩究鐭?/span>
    2018-07-24 14:31
  • 缃戝墽銆婄櫧澶滆拷鍑躲€嬭鎸囦镜鐘憲浣滄潈 浼橀叿銆佺紪鍓ч煩鍐拌璧疯瘔
    2018-07-24 14:31
  • 鍗庝负鍙戝竷2019骞寸涓夊搴︿笟缁?钀ユ敹6018浜垮悓姣斿闀?4.4%
    2019-10-17 11:48